Abstract
Artificial intelligence (AI) based psychotherapeutic interventions are emerging as a promising approach to support mental health care. This study evaluated their effectiveness in reducing depressive, anxiety, and stress symptoms across 30 randomized controlled trials with over 6,100 participants from nine countries.
Results showed that AI interventions significantly reduced depressive symptoms immediately after treatment, with a medium effect size, and maintained smaller but meaningful improvements at 6-12 months. Participants with depression benefited the most, while effects on anxiety and stress were less pronounced.
These findings indicate that AI-based psychotherapy can effectively complement traditional care for depression, providing an accessible tool to improve mental health outcomes. Continued research with long-term follow-up is needed to confirm these effects and explore strategies to enhance impact on anxiety and stress.
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